I had 285/75-16 MTs for a while. You have to do a ton of fender and bumper trimming up front. Was not an issue for me. I did not mind. I also had to move the washer reservoir because the tires were hitting the washer motor at full lock. After all the trimming and moving, and all the lift I have, I would still rub at full lock with the slightest of flex. Oh, and the MPGs sucked with those monsters on there with stock 3.73 gears. Average was about 13 - 15 on the highway. Power loss was extreme too. Jeep would downshift just to go over a simple overpass on the highway, or when pushing a 10-15 MPH headwind.
265/75-16 is much better now. But I still need to re-gear to 4.10s