Towing
Careful of that crosswind on I-40, and be careful coming through Oklahoma and Arkansas, you're going to get bounced all over the place. The shorter wheelbase of the Liberty does make it less rough than in my longer, stiffer springed F-250 work truck.
Tennessee has to be the worst part of I-40 as far as traffic goes. Memphis, Nashville and Knoxville are almost always under road construction and they're all full of crazy rednecks that think they're NASCAR drivers. They'll put you into the wall, seriously.
I can make it from Bristol, TN (right on the TN/VA state line) to Bakersfield, CA in 44 hours. I usually split it up into 3 days, 17-17-10.
I try to stay in Holiday Inn Expresses. Those are the only hotels that are always nice, I've never had a problem on I-40, or anywhere for that matter. The other hotel chains seem to be hit and miss when it comes to quality on I-40.
I-40 from Los Angeles to Oklahoma City is Historic Route 66, it turns north at OKC and heads to Chicago. They're are many tourist traps, most of the town along I-40 only exist becuase they have a gas station, a hotel, and something to lure the public in. There's the world's largest prairie dog, and the Cadillac garden, and many more.
The biggest trick is to keep yourself entertained. There isn't much scenery to look at and everything is flat and boring. I highly recommend SIRIUS, some good CD's and some books on tape. I think I'm going to try to relearn Spanish on my next trip. I moved out of Cali when I was 11, 15 years ago, and have forgotten all I knew.