I've been told there's one other possibility, by a couple friends that frequent other forums - that it's not a problem with the rear diff, but a problem with the rear suspension - more specifically, with sound isolation for the rear diff.
I've got similar symptoms - around 50 to 52K miles, started getting what was either driveline or tire noise faintly at highway speeds. It's gotten progressively louder such that it's faintly audible at street speeds, and quite audible at highway speeds.
I've went thru nearly the whole range of possibilities - front end alignment, rotating and balancing tires, pulling the front driveshaft, new tires (because the first shop that did an alignment effed it up and wore out two tires). Everything kept pointing to the rear diff or driveshaft.
But there is no vibration or other problems - just noise. I've driven other vehicles over the years that had a problem with the driveshaft or rear diff, and believe me, you would KNOW that something was out of whack - as the one gent said, you wouldn't make it 12K miles after the noise started if there was something seriously fubar with the diff.
My friends pointed me in the direction of the balljoint and bushings in the rear suspension being worn out - transmitting any noise from the rear diff directly into the cab. More specifically, the rear upper suspension arm - at the point of the "V", it's attached directly to the top of the diff by a balljoint, and to the body out at the ends of either arm via rubber bushings. If the balljoint and bushings go south, you've got a direct path for any noise from the diff to be transmitted directly to the cabin - like sitting inside an echo chamber.
From what I've checked, a new balljoint will run from $40 to $60 depending on which brand you get, and the two rubber bushings $15 to $20 each.
Might be worth giving this a shot to get rid of the noise - if it works, that beats paying $500 to $1000 to get the rear diff rebuilt. Besides the fact that if that balljoint and bushings are worn out, your rear suspension isn't working correctly and can cause other problems such as handling and unusual tire wear.